In this paper, we determine the charge lattice of mutually local Wilson and ’t Hooft line operators for class S theories living on M5-branes wrapped on compact Riemann surfaces. The main ingredients of our analysis are the fundamental group of the N-cover of the Riemann surface, and a quantum constraint on the six-dimensional theory. This latter plays a central role in excluding some of the possible lattices and imposing consistency conditions on the charges. This construction gives a geometric explanation for the mutual locality among the lines, fixing their charge lattice and the structure of the four-dimensional gauge group.